Risk factors for the formation of oral allergy syndrome in children

Видання

Romanian Journal of Pediatrics

Анотація

<jats:p>Background and objectives. Oral allergy syndrome (OAS) is often undiagnosed in children because it is considered a condition that primarily affects adults. The aim of this study was to investigate the prevalence, risk factors, and clinical course of OAS in children. Materials and methods. A survey was conducted among 512 children aged 4 to 17 years, from which 87 (16.9%) children with confirmed OAS were identified by questionnaire, clinical symptoms, testing for the presence of specific IgE and positive skin prick tests. Results. Boys predominated in OAS group – 63.2% (χ2 = 11.43, p&lt;0.05). In the structure of sensitization of the examined children, pollinosis caused by beech tree pollen and weeds prevailed (52.5% and 39.6%, respectively). The most frequent adverse food reactions were associated with peanuts (67 out of 87; 77%) and apples (56 out of 87; 64.3%). Among vegetables, tomatoes (54 out of 87; 62.1%) and carrots (46 out of 87; 52.8%) were the most common triggers. Some children with OAS reacted to several causal plant allergens – 29 out of 87; 33.3%. Male gender, late manifestation of the disease, severe allergic history, sensitization to beech tree pollen were statistically significant risk factors for OAS in children. Conclusions. The main predictors for the development of OSA, clinical features of the course, frequency distribution of plant allergens and their combinations were identified, which allow for the early identification of children at increased risk of developing the syndrome and enable the timely implementation of treatment and preventive measures.</jats:p>

Автори

Tamila Sorokman; Snizhana Sokolnyk; Nadiia Cherney; Mykola Gingulyak; Valentina Ostapchuk